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Outcome 4 - Capacity building

Supporting best practice through education and training.

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  • Promote stakeholder understanding of the purpose and components of evaluations through education.  
  • Use novel validated risk evaluation methods and processes adopted by other regulators.
  • Conduct systematic peer reviews of evaluations and peer review exchange for more complex evaluations with international regulators.

Scientific capability

We will build on our strengths and capacity through:

  • implementing our science strategy 
  • adopting peer review processes that ensure scientific integrity
  • developing assessment tools and guidance 
  • engaging in national and international initiatives such as new assessment methodologies (NAMS)
  • exchanging information to align with international harmonisation efforts.

New assessment methodologies 

Consistent with international practice, we use a combination of methods and data sources to inform our chemical evaluations, and monitor developments in these areas, including:

  • quantitative structure activity/use relationships (QSAR/QSUR)
  • read-across
  • in chemico
  • in vitro
  • in vivo
  • adverse outcome pathways (AOPs)
  • -omic technologies.

Learn about the ban on the use of animal data

International and academic engagement

To maintain best practice, we will actively engage with our international counterparts:

  • ensuring that our skills and knowledge base keep pace with international developments
  • enhancing evaluation findings through data exchange, sharing of training materials and peer review 
  • using the International Uniform Chemical Information Database (IUCLID) and the Organisation for Economic Cooperation and Development (OECD) QSAR Toolbox).    

We will link with academic institutions to: 

  • strengthen our engagement with research and develop knowledge about chemicals 
  • develop new assessment tools and methodologies 
  • consolidate data  
  • improve our regulatory capability 
  • improve opportunities for knowledge transfer  
  • increase university students’ awareness of regulatory science as a career option.

Maximising use of information by applying chemical informatics! 

Chemical informatics is key to supporting the high-throughput and accelerated evaluation of large numbers of chemicals.

What is chemical informatics?

The regulatory application of chemical informatics involves:

  • organising
  • quality-assuring
  • visualising and 
  • applying large amounts of electronic information to support prioritisation, risk assessment, and recommendations for risk management of chemicals. 

Chemical informatics means we can maximise the use and re-use of large amounts of quality assured chemical information to optimise the resources we need to evaluate chemicals. It also helps us complete and publish high-quality chemical evaluations in a timely way. Work to further develop our existing capabilities in chemical informatics will be an essential part of delivering our evaluations.

Next: Leadership and engagement


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